Mediterr J Otol 2005:1(3):148-151

Acrokeratosis paraneoplastica (Bazex syndrome) with ear manifestation

Daniel Perez Plasencia, Jose María Cuyas Lazarich, Angel Ramos Macias

Department of Otolaryngology, Insular Universitary Hospital of Gran  Canaria. Canary Island. daniplasencia@yahoo.es

Acrokeratosis paraneoplastica or Bazex Syndrome is a paraneoplastic cutaneous syndrome which is most frequently associated with squamous cell carcinoma of the upper aerodigestive tract and characterized by psoriasiform lesions. Early recognition of the condition in its first stage may allow more effective treatment of the underlying tumour to be undertaken but  diagnosis of Bazex’ syndrome is very difficult at this initial moment.

We report a patient with a piriform sinus tumour where the lesions at ears and face help us for the diagnosis and where the treatment of the underlying neoplasm led to disappearance of the cutaneous symptoms.